Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0D6IU
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| Former ID |
DNC012597
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| Drug Name |
2-(1H-Indol-3-yl)-2-oxo-N-phenethyl-acetamide
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| Synonyms |
2-(1H-Indol-3-yl)-2-oxo-N-phenethyl-acetamide; USGVPHMVQJFJJD-UHFFFAOYSA-N; 2-(1H-indol-3-yl)-2-oxo-N-(2-phenylethyl)acetamide; 2-(1H-Indol-3-yl)-2-oxo-N-[2-phenylethyl]acetamide; AC1M2UTB; MLS001212145; CHEMBL68442; SCHEMBL4760802; MolPort-000-249-097; HMS3430C11; ZINC2815535; STK710826; AKOS000530675; MCULE-7691246998; 94209-12-8; BAS 04280191; SMR000518992; ST4091858; MLS-0351990.0002; 2-(1H-indol-3-yl)-2-oxo-N-phenethylacetamide; 2-indol-3-yl-2-oxo-N-(2-phenylethyl)acetamide; Acetamide, 2-(1H-indol-3-yl)-2-oxo-N-phenethyl-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C18H16N2O2
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| Canonical SMILES |
C1=CC=C(C=C1)CCNC(=O)C(=O)C2=CNC3=CC=CC=C32
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| InChI |
1S/C18H16N2O2/c21-17(15-12-20-16-9-5-4-8-14(15)16)18(22)19-11-10-13-6-2-1-3-7-13/h1-9,12,20H,10-11H2,(H,19,22)
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| InChIKey |
USGVPHMVQJFJJD-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| GABA(A) receptor gamma-2 (GABRG2) | Target Info | Inhibitor | [1] | |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||
| Iron uptake and transport | ||||
| SIDS Susceptibility Pathways | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Benzodiazepine receptor affinity and interaction of some N-(indol-3-ylglyoxylyl)amine derivatives. J Med Chem. 1992 Jun 12;35(12):2214-20. | |||
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