Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0D1JP
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| Former ID |
DIB007686
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| Drug Name |
WR-279396
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| Synonyms |
Gentamicin sulfate mixture with paromomycin sulfate; 155379-51-4; Paromomycin/Gentamicin; Gentamicin / paromomycin; Paromomycin / Gentamicin; WR279396; paromomycin+gentamicin topical cream; Gentamicin sulfate / paromomycin sulfate; WR 279396; WR 279,396; WR-279,396; Gentamicin sulfate - paromomycin sulfate mixt.; DTXSID40165884; D-Streptamine, O-2-amino-2-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(O-2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl-(1-3)-beta-D-ribofuranosyl-(1-5))-2-deoxy-, sulfate (salt), mixt. with gentamicin
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| Drug Type |
Small molecular drug
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| Indication | Leishmania infection [ICD-11: 1F54.0; ICD-10: B55.0] | Phase 3 | [1] | |
| Company |
Walter Reed Army Institute of Research
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| Structure |
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Download2D MOL |
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| Formula |
C44H92N10O29S2
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| Canonical SMILES |
CC(C1CCC(C(O1)OC2C(CC(C(C2O)OC3C(C(C(CO3)(C)O)NC)O)N)N)N)NC.C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)O)N)OC3C(C(C(O3)CO)OC4C(C(C(C(O4)CN)O)O)N)O)O)N.OS(=O)(=O)O.OS(=O)(=O)O
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| InChI |
1S/C23H45N5O14.C21H43N5O7.2H2O4S/c24-2-7-13(32)15(34)10(27)21(37-7)41-19-9(4-30)39-23(17(19)36)42-20-12(31)5(25)1-6(26)18(20)40-22-11(28)16(35)14(33)8(3-29)38-22;1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20;2*1-5(2,3)4/h5-23,29-36H,1-4,24-28H2;9-20,25-29H,5-8,22-24H2,1-4H3;2*(H2,1,2,3,4)/t5-,6+,7+,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18?,19-,20-,21-,22-,23?;;;/m1.../s1
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| InChIKey |
AENMFAVRQFFUDK-OOVPIQBXSA-N
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| CAS Number |
CAS 155379-51-4
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00606580) Phase 3 Study to Evaluate WR 279,396 vs. Paromomycin Alone to Treat Cutaneous Leishmaniasis (in Tunisia). U.S. National Institutes of Health. | |||
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