Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0D1CL
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| Former ID |
DNCL002574
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| Drug Name |
MB07133
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| Synonyms |
MB-7133; MB-07133; 685111-92-6; CHEMBL218922; SCHEMBL12132117; HY-16311; CS-0006286; Z-3285; 2(1H)-PYRIMIDINONE, 4-AMINO-1-[5-O-[(2R,4S)-2-OXIDO-4-(4-PYRIDINYL)-1,3,2-DIOXAPHOSPHORINAN-2-YL]-BETA-D-ARABINOFURANOSYL]-
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| Drug Type |
Small molecular drug
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| Indication | Hepatocellular carcinoma [ICD-11: 2C12.02; ICD-10: C22.0; ICD-9: 155] | Phase 1/2 | [1] | |
| Company |
Ligand Pharmaceuticals
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| Structure |
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Download2D MOL |
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| Formula |
C17H21N4O8P
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| Canonical SMILES |
C1COP(=O)(OC1C2=CC=NC=C2)OCC3C(C(C(O3)N4C=CC(=NC4=O)N)O)O
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| InChI |
1S/C17H21N4O8P/c18-13-3-7-21(17(24)20-13)16-15(23)14(22)12(28-16)9-27-30(25)26-8-4-11(29-30)10-1-5-19-6-2-10/h1-3,5-7,11-12,14-16,22-23H,4,8-9H2,(H2,18,20,24)/t11-,12+,14+,15-,16+,30?/m0/s1
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| InChIKey |
HOAHIHGOMCBTFW-WUTQSZGESA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00073736) Safety and Tolerability of I.V. Infusion of MB07133 in Patients With Unresectable Hepatocellular Carcinoma. U.S. National Institutes of Health. | |||
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