Drug Information
Drug General Information | Top | |||
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Drug ID |
D0D0OX
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Former ID |
DNC009244
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Drug Name |
2,7-Bis(propionamido)anthraquinone
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Synonyms |
2,7-Bis(propionamido)anthraquinone; SCHEMBL4299908; CHEMBL481176
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C20H18N2O4
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Canonical SMILES |
CCC(=O)NC1=CC2=C(C=C1)C(=O)C3=C(C2=O)C=C(C=C3)NC(=O)CC
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InChI |
1S/C20H18N2O4/c1-3-17(23)21-11-5-7-13-15(9-11)20(26)16-10-12(22-18(24)4-2)6-8-14(16)19(13)25/h5-10H,3-4H2,1-2H3,(H,21,23)(H,22,24)
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InChIKey |
FNUQOQZYSRMGQN-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | TERT messenger RNA (TERT mRNA) | Target Info | Inhibitor | [1] |
KEGG Pathway | HTLV-I infection | |||
NetPath Pathway | IL2 Signaling Pathway | |||
Pathway Interaction Database | Validated targets of C-MYC transcriptional activation | |||
Regulation of Telomerase | ||||
IL2 signaling events mediated by PI3K | ||||
Regulation of nuclear beta catenin signaling and target gene transcription | ||||
HIF-1-alpha transcription factor network | ||||
Reactome | Formation of the beta-catenin:TCF transactivating complex | |||
WikiPathways | TGF beta Signaling Pathway | |||
miR-targeted genes in lymphocytes - TarBase | ||||
miR-targeted genes in epithelium - TarBase | ||||
Telomere Maintenance |
References | Top | |||
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REF 1 | Synthesis, human telomerase inhibition and anti-proliferative studies of a series of 2,7-bis-substituted amido-anthraquinone derivatives. Bioorg Med Chem. 2008 Jul 15;16(14):6976-86. |
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