Drug Information
Drug General Information | Top | |||
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Drug ID |
D0CZ1Q
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Former ID |
DAP001185
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Drug Name |
Desoximetasone
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Synonyms |
Desoximetasona; Desoximetasonum; Topicort; HOE-304; R-2113; Topicort (TN); Topicort Emollient (TN); A-41-304; Desoximetasone (USP/INN); (11beta,16alpha)-9-Fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione; (8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-3-one; 9-Fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione; 9alpha-fluoro-16alpha-methyl-Delta(1)-corticosterone
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Drug Type |
Small molecular drug
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Indication | Inflammation [ICD-11: 1A00-CA43.1] | Approved | [1], [2] | |
Therapeutic Class |
Antiinflammatory Agents
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Structure |
Download2D MOL |
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Formula |
C22H29FO4
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Canonical SMILES |
CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1C(=O)CO)C)O)F)C
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InChI |
1S/C22H29FO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-21(13,3)22(15,23)18(27)10-20(16,2)19(12)17(26)11-24/h6-7,9,12,15-16,18-19,24,27H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,18+,19-,20+,21+,22+/m1/s1
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InChIKey |
VWVSBHGCDBMOOT-IIEHVVJPSA-N
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CAS Number |
CAS 140218-14-0
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PubChem Compound ID | ||||
PubChem Substance ID |
855924, 7979049, 11056248, 15498318, 17397790, 29215017, 39340795, 46386959, 46506793, 50812429, 56423147, 57359344, 71840211, 92308575, 96080668, 103716863, 114155190, 124659098, 124801450, 134224923, 134338430, 134975313, 135829542, 137005253, 139999920, 144089052, 144204440, 160963892, 162184623, 163133993, 163835780, 164824559, 170464795, 172080493, 175268184, 178103646, 179296010, 210275697, 210281356, 224692518, 226396256, 241062747, 252090887, 252316558, 252390993
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ChEBI ID |
CHEBI:691037
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ADReCS Drug ID | BADD_D00620 | |||
SuperDrug ATC ID |
D07AC03; D07XC02
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SuperDrug CAS ID |
cas=000382672
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Target and Pathway | Top | |||
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Target(s) | Steroid hormone receptor ERR (ESRR) | Target Info | Modulator | [3] |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7067). | |||
REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 073193. | |||
REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. |
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