Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0CU9Y
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| Former ID |
DNC012962
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| Drug Name |
(S)-2-amino-2-o-tolylacetic acid
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| Synonyms |
(S)-Amino-o-tolyl-acetic acid; 339274-33-8; CHEMBL204179; (S)-2-AMINO-2-(O-TOLYL)ACETIC ACID; (2S)-2-amino-2-(2-methylphenyl)acetic acid; (S)-2-amino-2-o-tolylacetic acid; 2-Methyl-L-phenylglycine; AC1LT3T3; SCHEMBL3611200; FLYIRERUSAMCDQ-QMMMGPOBSA-N; ZINC4202377; BDBM50179691; AKOS006284304; AB30505; SC-21704; AJ-48395; AB1006782
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C9H11NO2
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| Canonical SMILES |
CC1=CC=CC=C1C(C(=O)O)N
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| InChI |
1S/C9H11NO2/c1-6-4-2-3-5-7(6)8(10)9(11)12/h2-5,8H,10H2,1H3,(H,11,12)/t8-/m0/s1
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| InChIKey |
FLYIRERUSAMCDQ-QMMMGPOBSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated calcium channel alpha-2/delta-1 (CACNA2D1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | MAPK signaling pathway | |||
| Cardiac muscle contraction | ||||
| Adrenergic signaling in cardiomyocytes | ||||
| Oxytocin signaling pathway | ||||
| Hypertrophic cardiomyopathy (HCM) | ||||
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | ||||
| Dilated cardiomyopathy | ||||
| Panther Pathway | Muscarinic acetylcholine receptor 2 and 4 signaling pathway | |||
| WikiPathways | Arrhythmogenic Right Ventricular Cardiomyopathy | |||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1138-41. | |||
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