Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0CI3Z
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| Drug Name |
AZD5462
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| Synonyms |
AZD5462; SCHEMBL24515489; HY-148087; CS-0610674
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| Drug Type |
Small molecule
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| Indication | Cardiovascular disease [ICD-11: BA00-BE2Z] | Phase 1 | [1] | |
| Company |
AstraZeneca
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| Structure |
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Download2D MOL |
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| Formula |
C30H41FN2O6
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| Canonical SMILES |
CC1(CCC1)CNC(=O)C2C3CCC(C3)C2NC(=O)C4=CC(=C(C=C4OC)F)OC5CCC(CC5)(C)C(=O)O
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| InChI |
InChI=1S/C30H41FN2O6/c1-29(9-4-10-29)16-32-27(35)24-17-5-6-18(13-17)25(24)33-26(34)20-14-23(21(31)15-22(20)38-3)39-19-7-11-30(2,12-8-19)28(36)37/h14-15,17-19,24-25H,4-13,16H2,1-3H3,(H,32,35)(H,33,34)(H,36,37)/t17-,18+,19?,24+,25-,30?/m1/s1
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| InChIKey |
LYUYYIGCZIZIGF-SRHODNEWSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Relaxin receptor 1 (RXFP1) | Target Info | Agonist | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT05512806) A Randomized, 6-period, 6-treatment, Single-Dose, Crossover Study to Assess the Pharmacokinetics of AZD5462 Film-coated Tablet Formulation, to Assess the Relative Bioavailability of AZD5462 Film-coated Tablet Formulation vs Oral Solution, and to Assess the Influence of Food on the Pharmacokinetics of AZD5462 in Healthy Participants. U.S.National Institutes of Health. | |||
| REF 2 | Clinical pipeline report, company report or official report of AstraZeneca | |||
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