Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0CA3J
|
|||
| Former ID |
DNCL001786
|
|||
| Drug Name |
GSK568859
|
|||
| Indication | Arteriosclerosis [ICD-11: BD40; ICD-10: I70] | Discontinued in Phase 1 | [1] | |
| Company |
GlaxoSmithKline
|
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Platelet-activating factor acetylhydrolase (PLA2G7) | Target Info | Modulator | [2] |
| KEGG Pathway | Ether lipid metabolism | |||
| Metabolic pathways | ||||
| Biosynthesis of antibiotics | ||||
| Pathway Interaction Database | Lissencephaly gene (LIS1) in neuronal migration and development | |||
| WikiPathways | IL1 and megakaryotyces in obesity | |||
| Synthesis, Secretion, and Deacylation of Ghrelin | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025982) | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1432). | |||
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