Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0C9XA
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| Former ID |
DPR000001
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| Drug Name |
GSK683699
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| Synonyms |
4-Aminobutanoic acid; 4-aminobutyric acid; GABA; gamma-aminobutyric acid; 1956/12/2; Piperidic acid; Piperidinic acid; Aminalon; Mielogen; Gammalon; Gaballon; butanoic acid, 4-amino-; Mielomade; Gammalone; Gamarex; Gammasol; Gammar; Reanal; Immu-G; gamma-amino-n-butyric acid; gamma-Aminobutanoic acid; Butyric acid, 4-amino-; Gamastan; Gammagee; Gamulin; 4-aminobutyrate; omega-Aminobutyric acid; gamma-Aminobutyric acid; 3-Carboxypropylamine; gamma-Aminobuttersaeure; 4-amino-butanoic acid; gamma-Amino butyric acid; GAMMA-AMINO-BUTANOIC ACID
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| Drug Type |
Small molecular drug
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| Indication | Inflammatory bowel disease [ICD-11: DD72; ICD-10: K52.3] | Phase 2 | [1] | |
| Company |
GSK; Tanabe
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| Structure |
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Download2D MOL |
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| Formula |
C4H9NO2
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| Canonical SMILES |
C(CC(=O)O)CN
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| InChI |
1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)
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| InChIKey |
BTCSSZJGUNDROE-UHFFFAOYSA-N
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| CAS Number |
CAS 56-12-2
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| PubChem Compound ID | ||||
| PubChem Substance ID |
3628, 87901, 90737, 99151, 102735, 588080, 841798, 3131894, 5006226, 7847126, 7885654, 7979337, 8138105, 8138144, 8138251, 8138279, 8139983, 8145275, 8149630, 8150467, 10527343, 11110722, 11113457, 11335791, 11361030, 11362843, 11365405, 11367967, 11372289, 11374436, 11376129, 11462002, 11484732, 11489024, 11491200, 11492624, 11493863, 14818111, 17404570, 24278167, 24424261, 24424263, 24438498, 24701168, 24715057, 24891025, 25623205, 26512225, 26612021, 26679211
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| ChEBI ID |
CHEBI:16865
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| ADReCS Drug ID | BADD_D01002 | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Emerging drugs to treat Crohn's disease. Expert Opin Emerg Drugs. 2007 Mar;12(1):49-59. | |||
| REF 2 | Novel secoergoline derivatives inhibit both GABA and glutamate uptake in rat brain homogenates: synthesis, in vitro pharmacology, and modeling. J Med Chem. 2004 Nov 4;47(23):5620-9. | |||
| REF 3 | Epimeric cis-decahydroquinoline-5-carboxylic acids: effects on gamma-aminobutyric acid uptake and receptor binding in vitro. J Med Chem. 1981 Jul;24(7):788-94. | |||
| REF 4 | 3-demethoxy-3-glycosylaminothiocolchicines: Synthesis of a new class of putative muscle relaxant compounds. J Med Chem. 2006 Sep 7;49(18):5571-7. | |||
| REF 5 | New anticonvulsants: Schiff bases of gamma-aminobutyric acid and gamma-aminobutyramide. J Med Chem. 1980 Jun;23(6):702-4. | |||
| REF 6 | 3-Thienyl- and 3-furylaminobutyric acids. Synthesis and binding GABAB receptor studies. J Med Chem. 1991 Aug;34(8):2557-60. | |||
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