Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0C8AL
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| Former ID |
DIB010123
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| Drug Name |
Fluoropeptide vaccine
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| Synonyms |
FP-01; Fluoropeptide vaccine (influenza); Fluoropeptide vaccine (influenza), Immune Targeting Systems
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| Drug Type |
Vaccine
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| Indication | Influenza virus infection [ICD-11: 1E30-1E32] | Phase 2 | [1] | |
| Company |
Immune Targeting Systems Ltd
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | T-cell surface glycoprotein CD4 (CD4) | Target Info | . | [2] |
| T-cell surface glycoprotein CD8 (CD8) | Target Info | . | [2] | |
| KEGG Pathway | Cell adhesion molecules (CAMs) | |||
| Antigen processing and presentation | ||||
| Hematopoietic cell lineage | ||||
| T cell receptor signaling pathway | ||||
| Primary immunodeficiency | ||||
| NetPath Pathway | Leptin Signaling Pathway | |||
| Pathway Interaction Database | TCR signaling in naï | |||
| IL12-mediated signaling events | ||||
| CXCR4-mediated signaling events | ||||
| C-MYB transcription factor network | ||||
| IL23-mediated signaling events | ||||
| Arf1 pathway | ||||
| Notch-mediated HES/HEY network | ||||
| IL12 signaling mediated by STAT4 | ||||
| Reactome | Binding and entry of HIV virion | |||
| Phosphorylation of CD3 and TCR zeta chains | ||||
| Translocation of ZAP-70 to Immunological synapse | ||||
| Generation of second messenger molecules | ||||
| PD-1 signaling | ||||
| WikiPathways | TCR Signaling Pathway | |||
| Cytokines and Inflammatory Response | ||||
| Host Interactions of HIV factors | ||||
| Defensins | ||||
| HIV Life Cycle | ||||
| TCR signaling | ||||
| Costimulation by the CD28 family | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01703923) An Exploratory Study of FP01 Lozenges in Subjects With Chronic Refractory Cough. U.S. National Institutes of Health. | |||
| REF 2 | A novel peptide-based pan-influenza A vaccine: a double blind, randomised clinical trial of immunogenicity and safety. Vaccine. 2015 Jan 3;33(2):396-402. | |||
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