Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0C6DT
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| Former ID |
DAP000726
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| Drug Name |
Esomeprazole
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| Synonyms |
Esomeprazolum; Nexiam; Inexium paranova; Axagon (TN); Esomeprazole (INN); Esomeprazole [INN:BAN]; Esopral (TN); Inexium paranova (TN); Lucen (TN); Nexiam (TN); Nexium (TN); Sompraz (TN); Zoleri (TN); (S)-(-)-Omeprazole; (S)-Omeprazole; 5-Methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl)benzimidazole; 5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole; 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1-methyl-1H-benzimidazole
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| Drug Type |
Small molecular drug
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| Indication | Peptic ulcer [ICD-11: DA61] | Approved | [1], [2] | |
| Therapeutic Class |
Antiulcer Agents
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| Company |
AstraZeneca
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| Structure |
 |
Download2D MOL |
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| Formula |
C17H19N3O3S
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| Canonical SMILES |
CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC
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| InChI |
1S/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)/t24-/m0/s1
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| InChIKey |
SUBDBMMJDZJVOS-DEOSSOPVSA-N
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| CAS Number |
CAS 119141-88-7
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| PubChem Compound ID | ||||
| PubChem Substance ID |
591076, 14875947, 14900571, 44707139, 56394969, 80295315, 93166178, 96024613, 124759673, 124968856, 126525308, 126670961, 129288902, 129288903, 137001228, 137752931, 139533883, 152040240, 160825217, 163092495, 163384365, 163840367, 164044845, 175267781, 175269116, 175437905, 178102135, 189657728, 198993898, 204429634, 211535433, 223971225, 226409261, 246378786, 249855831, 250200763, 251886328, 251964001, 252074449, 252430137
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| ChEBI ID |
CHEBI:50275
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| ADReCS Drug ID | BADD_D00815 ; BADD_D00816 ; BADD_D00817 ; BADD_D00818 ; BADD_D01558 | |||
| SuperDrug ATC ID |
A02BC05
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| SuperDrug CAS ID |
cas=161973100
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Gastric H(+)/K(+) ATPase (Proton pump) | Target Info | Modulator | [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5488). | |||
| REF 2 | Esomeprazole: a review of its use in the management of gastric acid-related diseases in adults. Drugs. 2008;68(11):1571-607. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. | |||
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