Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0C3QE
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| Former ID |
DNC004630
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| Drug Name |
N-(5-Benzyloxy-isoquinolin-1-yl)-guanidine
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| Synonyms |
CHEMBL325094; N-(5-Benzyloxy-isoquinolin-1-yl)-guanidine; SCHEMBL6998909; KMGPZVZUHUMNQX-UHFFFAOYSA-N; BDBM50147411
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C17H16N4O
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| Canonical SMILES |
C1=CC=C(C=C1)COC2=CC=CC3=C2C=CN=C3N=C(N)N
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| InChI |
1S/C17H16N4O/c18-17(19)21-16-14-7-4-8-15(13(14)9-10-20-16)22-11-12-5-2-1-3-6-12/h1-10H,11H2,(H4,18,19,20,21)
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| InChIKey |
KMGPZVZUHUMNQX-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tissue-type plasminogen activator (PLAT) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Complement and coagulation cascades | |||
| Transcriptional misregulation in cancer | ||||
| NetPath Pathway | IL5 Signaling Pathway | |||
| Panther Pathway | Blood coagulation | |||
| Plasminogen activating cascade | ||||
| Pathwhiz Pathway | Coagulation | |||
| Pathway Interaction Database | amb2 Integrin signaling | |||
| Beta2 integrin cell surface interactions | ||||
| Reactome | Dissolution of Fibrin Clot | |||
| WikiPathways | Senescence and Autophagy in Cancer | |||
| Complement and Coagulation Cascades | ||||
| Endochondral Ossification | ||||
| Blood Clotting Cascade | ||||
| Dissolution of Fibrin Clot | ||||
| Folate Metabolism | ||||
| Vitamin B12 Metabolism | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Selective urokinase-type plasminogen activator (uPA) inhibitors. Part 3: 1-isoquinolinylguanidines. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3227-30. | |||
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