Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0BW4W
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| Former ID |
DIB013406
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| Drug Name |
Sutezolid
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| Synonyms |
PF-02341272; PF-2341272; PNU-100480; PNU-101244; PNU-101603; U-100480; U-101244; U-101603; U-94901
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| Drug Type |
Small molecular drug
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| Indication | Tuberculosis [ICD-11: 1B10-1B1Z; ICD-10: A15-A19, B90] | Phase 2 | [1] | |
| Company |
Sequella
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| Structure |
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Download2D MOL |
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| Formula |
C16H20FN3O3S
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| Canonical SMILES |
CC(=O)NCC1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCSCC3)F
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| InChI |
1S/C16H20FN3O3S/c1-11(21)18-9-13-10-20(16(22)23-13)12-2-3-15(14(17)8-12)19-4-6-24-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1
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| InChIKey |
FNDDDNOJWPQCBZ-ZDUSSCGKSA-N
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| CAS Number |
CAS 168828-58-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial Protein synthesis (Bact PROS) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01225640) A Study Of PNU-100480 In Newly Diagnosed, Treatment Sensitive Patients With Pulmonary Tuberculosis To Assess Early Bactericidal Activity (EBA) And Whole Blood Activity (WBA). U.S. National Institutes of Health. | |||
| REF 2 | Cellular pharmacodynamics of the novel biaryloxazolidinone radezolid: studies with infected phagocytic and nonphagocytic cells, using Staphylococcus aureus, Staphylococcus epidermidis, Listeria monocytogenes, and Legionella pneumophila. Antimicrob Agents Chemother. 2010 Jun;54(6):2549-59. | |||
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