Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0BB2F
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| Drug Name |
Pyrazole derivative 26
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| Synonyms |
PMID26161824-Compound-38
Click to Show/Hide
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| Drug Type |
Small molecular drug
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| Indication | Obesity [ICD-11: 5B81; ICD-10: E66; ICD-9: 278] | Patented | [1] | |
| Company |
GREEN CROSS CORPORATION LEE, Jinhwa KIM, Jeong Min CHANG, Chong-Hwan Jonathan LEE, Suk Ho SEO, Hee Jeong KANG, Suk Youn SONG, Kwang-Seop KIM, Jong Yup KIM, Min Ju LEE, Sung-Han AHN, Kwang-Woo JUNG, Myung Eu
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| Structure |
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Download2D MOL |
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| Formula |
C25H17Cl3F3N7O
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| Canonical SMILES |
C1CC(C1)(C2=NN=C(O2)C3=NN(C(=C3CN4C=NC=N4)C5=CC=C(C=C5)Cl)C6=C(C=C(C=C6)Cl)Cl)C(F)(F)F
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| InChI |
1S/C25H17Cl3F3N7O/c26-15-4-2-14(3-5-15)21-17(11-37-13-32-12-33-37)20(36-38(21)19-7-6-16(27)10-18(19)28)22-34-35-23(39-22)24(8-1-9-24)25(29,30)31/h2-7,10,12-13H,1,8-9,11H2
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| InChIKey |
MXDYVLWGDAKEMQ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cannabinoid receptor 1 (CB1) | Target Info | Antagonist | [1] |
| Target's Patent Info | Cannabinoid receptor 1 (CB1) | Target's Patent Info | [1] | |
| KEGG Pathway | Rap1 signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Retrograde endocannabinoid signaling | ||||
| Panther Pathway | Endogenous cannabinoid signaling | |||
| Pathway Interaction Database | N-cadherin signaling events | |||
| Reactome | Class A/1 (Rhodopsin-like receptors) | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Small Ligand GPCRs | ||||
| BDNF signaling pathway | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | A comprehensive patents review on cannabinoid 1 receptor antagonists as antiobesity agents. Expert Opin Ther Pat. 2015 Oct;25(10):1093-116. | |||
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