Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0B9ZK
|
|||
Former ID |
DNC008733
|
|||
Drug Name |
3-methoxy-9-aminomethyl-9,10-dihydroanthracene
|
|||
Synonyms |
3-METHOXY-9-AMINOMETHYL-9,10-DIHYDROANTHRACENE; CHEMBL83081; 1075741-20-6; DTXSID10648836; BDBM50131086; 3-Methoxy-9,10-dihydroanthracene-9-methanamine; 1-(3-Methoxy-9,10-dihydroanthracen-9-yl)methanamine
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C16H17NO
|
|||
Canonical SMILES |
COC1=CC2=C(C=C1)C(C3=CC=CC=C3C2)CN
|
|||
InChI |
1S/C16H17NO/c1-18-13-6-7-15-12(9-13)8-11-4-2-3-5-14(11)16(15)10-17/h2-7,9,16H,8,10,17H2,1H3
|
|||
InChIKey |
DTEPCKRLYVEVEM-UHFFFAOYSA-N
|
|||
CAS Number |
CAS 1075741-20-6
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | 5-HT 2A receptor (HTR2A) | Target Info | Inhibitor | [1] |
KEGG Pathway | Calcium signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Gap junction | ||||
Serotonergic synapse | ||||
Inflammatory mediator regulation of TRP channels | ||||
Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
Reactome | Serotonin receptors | |||
G alpha (q) signalling events | ||||
WikiPathways | Serotonin Receptor 2 and STAT3 Signaling | |||
Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
SIDS Susceptibility Pathways | ||||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
GPCRs, Other |
References | Top | |||
---|---|---|---|---|
REF 1 | Methoxy-substituted 9-aminomethyl-9,10-dihydroanthracene (AMDA) derivatives exhibit differential binding affinities at the 5-HT(2A) receptor. Bioorg Med Chem Lett. 2008 Oct 1;18(19):5268-71. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.