Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0B8NW
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| Former ID |
DIB016412
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| Drug Name |
ICA-1
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| Synonyms |
PKC-iota inhibitor (cancer), Inhibition therapeutics
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Terminated | [1] | |
| Company |
AlumiFuel Power Corp
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| Structure |
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Download2D MOL |
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| Formula |
C10H17N4O7P
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| Canonical SMILES |
C1C(C(C(C1N2C=NC(=C2N)C(=O)N)O)O)COP(=O)(O)O
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| InChI |
1S/C10H17N4O7P/c11-9-6(10(12)17)13-3-14(9)5-1-4(7(15)8(5)16)2-21-22(18,19)20/h3-5,7-8,15-16H,1-2,11H2,(H2,12,17)(H2,18,19,20)/t4-,5-,7-,8+/m0/s1
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| InChIKey |
VFGPDCAAUMRRSL-BKMCOVHNSA-N
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027592) | |||
| REF 2 | A novel PKC- inhibitor abrogates cell proliferation and induces apoptosis in neuroblastoma. Int J Biochem Cell Biol. 2011 May;43(5):784-94. | |||
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