Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0B7LU
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| Former ID |
DIB012537
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| Drug Name |
CX-5461
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| Synonyms |
RNA ppolymerase I inhibitor (oral, cancer), Cylene
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| Drug Type |
Small molecular drug
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Investigative | [1] | |
| Company |
Cylene Pharmaceuticals Inc
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| Structure |
 |
Download2D MOL |
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| Formula |
C27H27N7O2S
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| Canonical SMILES |
CC1=CN=C(C=N1)CNC(=O)C2=C3N(C4=CC=CC=C4S3)C5=C(C2=O)C=CC(=N5)N6CCCN(CC6)C
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| InChI |
1S/C27H27N7O2S/c1-17-14-29-18(15-28-17)16-30-26(36)23-24(35)19-8-9-22(33-11-5-10-32(2)12-13-33)31-25(19)34-20-6-3-4-7-21(20)37-27(23)34/h3-4,6-9,14-15H,5,10-13,16H2,1-2H3,(H,30,36)
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| InChIKey |
XGPBJCHFROADCK-UHFFFAOYSA-N
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| CAS Number |
CAS 1138549-36-6
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| PubChem Compound ID | ||||
| PubChem Substance ID |
58091691, 85933120, 136340313, 136349551, 136367682, 137499754, 138725846, 144115862, 152255062, 152258539, 160647373, 162011352, 162038048, 162205144, 172650759, 174007361, 174526290, 185990482, 198947700, 223382414, 237346804, 242060320, 245368226, 251963050, 252110178, 252160793, 252215208, 252451783
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| ChEBI ID |
CHEBI:95090
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954. | |||
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