Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0B6OG
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| Former ID |
DIB009363
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| Drug Name |
BBT-007
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| Synonyms |
Long-acting GM-CSF (PEGylated, neutropenia), Bolder BioTechnology
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| Indication | Neutropenia [ICD-11: 4B00.0; ICD-9: 288] | Investigative | [1] | |
| Company |
Bolder BioTechnology Inc
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GMCSFR-alpha (CSF2RA) | Target Info | Stimulator | [1] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| Jak-STAT signaling pathway | ||||
| Hematopoietic cell lineage | ||||
| Pathways in cancer | ||||
| NetPath Pathway | IL3 Signaling Pathway | |||
| RANKL Signaling Pathway | ||||
| Pathway Interaction Database | GMCSF-mediated signaling events | |||
| Alpha9 beta1 integrin signaling events | ||||
| Reactome | GPVI-mediated activation cascade | |||
| G beta:gamma signalling through PI3Kgamma | ||||
| Interleukin-3, 5 and GM-CSF signaling | ||||
| RAF/MAP kinase cascade | ||||
| Surfactant metabolism | ||||
| Interleukin receptor SHC signaling | ||||
| WikiPathways | Interleukin-2 signaling | |||
| Interleukin-3, 5 and GM-CSF signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1707). | |||
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