Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0B3AR
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| Former ID |
DIB021088
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| Drug Name |
TRIM
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| Synonyms |
Trim; 25371-96-4; 1-[2-(trifluoromethyl)phenyl]imidazole; 1-(2-Trifluoromethylphenyl)imidazole; 1-(2-(Trifluoromethyl)phenyl)-1H-imidazole; 1-[2-(Trifluoromethyl)phenyl]-1H-imidazole; CHEMBL277525; WZBWBNCQUTXYEL-UHFFFAOYSA-N; NCGC00016047-03; 1H-Imidazole,1-[2-(trifluoromethyl)phenyl]-; DSSTox_RID_80756; DSSTox_CID_25217; DSSTox_GSID_45217; [2-(trifluoromethyl)phenyl]imidazole; 1-TRIM; CAS-25371-96-4; SR-01000076173; PubChem6489; Tocris-0919; ACMC-1CKKY; AC1L1BAW; AC1Q4JVD; Lopac-T-7313; Lopac0_001200; KBioSS_000064
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C10H7F3N2
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| Canonical SMILES |
C1=CC=C(C(=C1)C(F)(F)F)N2C=CN=C2
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| InChI |
1S/C10H7F3N2/c11-10(12,13)8-3-1-2-4-9(8)15-6-5-14-7-15/h1-7H
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| InChIKey |
WZBWBNCQUTXYEL-UHFFFAOYSA-N
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| CAS Number |
CAS 25371-96-4
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| PubChem Compound ID | ||||
| PubChem Substance ID |
954300, 3153185, 5286685, 8151108, 10515750, 11111914, 11113789, 11121409, 11121889, 11362478, 11365040, 11367602, 11370227, 11370228, 11373203, 11375764, 15195755, 17405754, 24278754, 24439700, 26612741, 26747136, 26751969, 47291232, 47515415, 47810860, 48259353, 48498626, 50104641, 50104642, 50104643, 50104644, 53778306, 53800881, 57268339, 57320882, 74918018, 85231271, 85788746, 87636903, 90340837, 92303203, 92309760, 99300674, 99302192, 103086861, 103150979, 103179142, 103996308, 104297509
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| ChEBI ID |
CHEBI:109530
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Transient receptor potential cation channel V2 (TRPV2) | Target Info | Blocker (channel blocker) | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4331). | |||
| REF 2 | Pharmacological characterization and molecular determinants of the activation of transient receptor potential V2 channel orthologs by 2-aminoethoxy... Mol Pharmacol. 2007 Nov;72(5):1258-68. | |||
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