Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0B1LR
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| Former ID |
DNC010958
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| Drug Name |
2-(thiazol-4-yl)-1H-benzo[d]imidazol-5-amine
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| Synonyms |
1H-Benzimidazol-5-amine, 2-(4-thiazolyl)-; CHEMBL370420; 25893-06-5; 5-Aminothiabendazole; 5-amino-2-(thiazol-4-yl)-1H-benzimidazole; 2-(4-Thiazolyl)-1H-benzimidazol-5-amine; AC1Q4XVD; 2-(thiazol-4-yl)-1H-benzo[d]imidazol-5-amine; AC1L35H8; SCHEMBL4367564; CTK7D8516; CUDHOGCHOXYXRZ-UHFFFAOYSA-N; MolPort-004-293-518; ZINC13679482; BDBM50180749; AKOS000129404; MCULE-2929987645; 5-amino-2-thiazol-4-yl-1H-benzoimidazole; 2-Thiazol-4-yl-3H-benzoimidazol-5-ylamine; 2-(1,3-thiazol-4-yl)-3H-benzimidazol-5-amine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H8N4S
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| Canonical SMILES |
C1=CC2=C(C=C1N)NC(=N2)C3=CSC=N3
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| InChI |
1S/C10H8N4S/c11-6-1-2-7-8(3-6)14-10(13-7)9-4-15-5-12-9/h1-5H,11H2,(H,13,14)
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| InChIKey |
CUDHOGCHOXYXRZ-UHFFFAOYSA-N
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| CAS Number |
CAS 25893-06-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Methionine aminopeptidase 2 (METAP2) | Target Info | Inhibitor | [1] |
| Reactome | Inactivation, recovery and regulation of the phototransduction cascade | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Subtype-selectivity of metal-dependent methionine aminopeptidase inhibitors, Bioorg. Med. Chem. Lett. 20(14):4038-4044 (2010). | |||
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