Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0B0RZ
|
|||
| Drug Name |
GRL-0667
|
|||
| Synonyms |
BDBM50007789; CHEMBL1173044; GRM; Q27460878; SCHEMBL7938638
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Severe acute respiratory syndrome (SARS) [ICD-11: 1D65] | Investigative | [1] | |
| Therapeutic Class |
Antiviral Agents
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C26H28N2O3
|
|||
| Canonical SMILES |
CC(C1=CC=CC2=CC=CC=C21)N3CCC(CC3)C(=O)NCC4=CC5=C(C=C4)OCO5
|
|||
| InChI |
1S/C26H28N2O3/c1-18(22-8-4-6-20-5-2-3-7-23(20)22)28-13-11-21(12-14-28)26(29)27-16-19-9-10-24-25(15-19)31-17-30-24/h2-10,15,18,21H,11-14,16-17H2,1H3,(H,27,29)/t18-/m1/s1
|
|||
| InChIKey |
IVXBCFLWMPMSAP-GOSISDBHSA-N
|
|||
| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:149790
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | SARS-CoV papain-like proteinase (PL-PRO) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Severe acute respiratory syndrome coronavirus papain-like novel protease inhibitors: design, synthesis, protein-ligand X-ray structure and biologic... J Med Chem. 2010 Jul 8;53(13):4968-79. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.