Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0AY7O
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| Drug Name |
Polyinosinic:polycytidylic acid
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| Synonyms |
NSC-120,949; PI:C; Poly 1-poly-c; Poly C poly I; Poly I:poly C; Poly IC; Poly rI:poly rC; Poly(I).poly(C); Poly(I).poly(C) complex; Poly(I:C); Poly(rI)-poly(rC); Poly(rI).(rC); Poly(rI).poly(rC); Poly(rI:rC); Polycytid; Polyinosinic acid.polycytidylic acid; Polyinosinic-polycyticylic acid complex; Polyriboinosinic acid:polyribocytidylic acid; polyinosine-polycytosine
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| Drug Type |
Small molecular drug
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| Indication | Middle East Respiratory Syndrome (MERS) [ICD-11: 1D64] | Investigative | [1] | |
| Therapeutic Class |
Antiviral Agents
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| Structure |
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Download2D MOL
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| Formula |
C19H27N7O16P2
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| Canonical SMILES |
C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COP(=O)(O)O)O)O
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| InChI |
1S/C10H13N4O8P.C9H14N3O8P/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20);1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,10-;4-,6-,7-,8-/m11/s1
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| InChIKey |
ACEVNMQDUCOKHT-ZLOOHWKQSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | HUMAN toll-like receptor 3 (TLR3) | Target Info | Agonist | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Middle East Respiratory Syndrome Coronavirus (MERS-CoV): Infection, Immunological Response, and Vaccine Development. J Immunol Res. 2019 Apr 7;2019:6491738. doi: 10.1155/2019/6491738. | |||
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