Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0AW6C
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| Former ID |
DNC006451
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| Drug Name |
N'-(phenylsulfonyl)benzofuran-2-carbohydrazide
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| Synonyms |
CHEMBL205220; SCHEMBL6240233; AMGAILKMHSFVNJ-UHFFFAOYSA-N; BDBM50172929; N''-(phenylsulfonyl)benzofuran-2-carbohydrazide; Benzofuran-2-carboxylic acid 2-(phenylsulfonyl)hydrazide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H12N2O4S
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| Canonical SMILES |
C1=CC=C(C=C1)S(=O)(=O)NNC(=O)C2=CC3=CC=CC=C3O2
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| InChI |
1S/C15H12N2O4S/c18-15(14-10-11-6-4-5-9-13(11)21-14)16-17-22(19,20)12-7-2-1-3-8-12/h1-10,17H,(H,16,18)
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| InChIKey |
AMGAILKMHSFVNJ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Branched-chain-amino-acid transaminase 2 (BCAT2) | Target Info | Inhibitor | [1] |
| BioCyc | Leucine degradation | |||
| Valine degradation | ||||
| Isoleucine degradation | ||||
| KEGG Pathway | Valine, leucine and isoleucine degradation | |||
| Valine, leucine and isoleucine biosynthesis | ||||
| Pantothenate and CoA biosynthesis | ||||
| Metabolic pathways | ||||
| Biosynthesis of antibiotics | ||||
| 2-Oxocarboxylic acid metabolism | ||||
| Biosynthesis of amino acids | ||||
| Panther Pathway | Alanine biosynthesis | |||
| Isoleucine biosynthesis | ||||
| Leucine biosynthesis | ||||
| Valine biosynthesis | ||||
| WikiPathways | Metabolism of amino acids and derivatives | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases. Bioorg Med Chem Lett. 2006 May 1;16(9):2337-40. | |||
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