Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0AW4P
|
|||
Former ID |
DNC007672
|
|||
Drug Name |
1,2-bis(3-fluorophenyl)-2-hydroxyethanon
|
|||
Synonyms |
CHEMBL396977; 1,2-bis(3-fluorophenyl)-2-hydroxyethanon; 1,2-bis(3-fluorophenyl)-2-hydroxy-ethanone; SCHEMBL11382156; BDBM50209422
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C14H10F2O2
|
|||
Canonical SMILES |
C1=CC(=CC(=C1)F)C(C(=O)C2=CC(=CC=C2)F)O
|
|||
InChI |
1S/C14H10F2O2/c15-11-5-1-3-9(7-11)13(17)14(18)10-4-2-6-12(16)8-10/h1-8,13,17H
|
|||
InChIKey |
AELVPDSJUJGTJH-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Liver carboxylesterase (CES1) | Target Info | Inhibitor | [1] |
KEGG Pathway | Drug metabolism - other enzymes | |||
Metabolic pathways | ||||
Pathway Interaction Database | E2F transcription factor network | |||
WikiPathways | NRF2 pathway | |||
Nuclear Receptors Meta-Pathway | ||||
Heroin metabolism | ||||
Irinotecan Pathway | ||||
Fluoropyrimidine Activity | ||||
Phase I biotransformations, non P450 |
References | Top | |||
---|---|---|---|---|
REF 1 | Analysis of the inhibition of mammalian carboxylesterases by novel fluorobenzoins and fluorobenzils. Bioorg Med Chem. 2007 Jun 1;15(11):3801-17. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.