Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0AQ3U
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| Drug Name |
PMID25666693-Compound-153
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| Drug Type |
Small molecular drug
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| Indication | Cancer related pain [ICD-11: MG30; ICD-10: R52.1, R52.2] | Patented | [1] | |
| Inflammatory pain [ICD-11: MG30.42; ICD-10: R52, G89] | Patented | [1] | ||
| Neuropathic pain [ICD-11: 8E43.0] | Patented | [1] | ||
| Osteoarthritis pain [ICD-11: MG30.31] | Patented | [1] | ||
| Company |
Amorepacific Corp
|
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| Structure |
 |
Download2D MOL |
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| Formula |
C22H16F8N2O4S
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| Canonical SMILES |
CC(C1=CC(=C(C(=C1)F)NS(=O)(=O)C)F)NC(=O)C2=CC=C(O2)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F
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| InChI |
1S/C22H16F8N2O4S/c1-10(11-7-15(23)19(16(24)8-11)32-37(2,34)35)31-20(33)18-4-3-17(36-18)12-5-13(21(25,26)27)9-14(6-12)22(28,29)30/h3-10,32H,1-2H3,(H,31,33)/t10-/m1/s1
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| InChIKey |
RGPMLUVMZUYQEJ-SNVBAGLBSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Transient receptor potential cation channel V1 (TRPV1) | Target Info | Antagonist | [1] |
| Target's Patent Info | Transient receptor potential cation channel V1 (TRPV1) | Target's Patent Info | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Inflammatory mediator regulation of TRP channels | ||||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Pathway Interaction Database | Trk receptor signaling mediated by the MAPK pathway | |||
| Trk receptor signaling mediated by PI3K and PLC-gamma | ||||
| Reactome | TRP channels | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Transient receptor potential vanilloid type 1 antagonists: a patent review (2011 - 2014).Expert Opin Ther Pat. 2015 Mar;25(3):291-318. | |||
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