Drug Information
Drug General Information | Top | |||
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Drug ID |
D0AO9S
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Former ID |
DAP000799
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Drug Name |
Enflurane
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Synonyms |
Alyrane; Efrane; Enflurano; Enfluranum; Enfran; Enlirane; Ethrane; Etran; Methylflurether; Abbott Brand of Enflurane; AstraZeneca Brand of Enflurane; Baxter Anaesthesia Brand of Enflurane; Pisa Brand of Enflurane; Zeneca Brand of Enflurane; Anesthetic 347; C 347; OHIO 347; Anesthetic Compound No. 347; Enflurane [Anaesthetics,volatile]; Enflurano [INN-Spanish]; Enfluranum [INN-Latin]; Ethrane (TN); Enflurane (JP15/USP/INN); Enflurane [USAN:BAN:INN:JAN]; Ether, 2-chloro-1,1,2-trifluoroethyl difluoromethyl; (+-)-2-Chloro-1,1,2-trifluoroethyl difluoromethyl ether; 2-Chloro-1,1,2-trifluoroethyl difluoromethyl ether; 2-Chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane
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Drug Type |
Small molecular drug
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Indication | Anaesthesia [ICD-11: 9A78.6; ICD-9: 338] | Approved | [1], [2] | |
Therapeutic Class |
Anesthetics
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Structure |
Download2D MOL |
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Formula |
C3H2ClF5O
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Canonical SMILES |
C(C(OC(F)F)(F)F)(F)Cl
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InChI |
1S/C3H2ClF5O/c4-1(5)3(8,9)10-2(6)7/h1-2H
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InChIKey |
JPGQOUSTVILISH-UHFFFAOYSA-N
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CAS Number |
CAS 13838-16-9
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PubChem Compound ID | ||||
PubChem Substance ID |
9719, 412027, 3159891, 3723211, 5141500, 7847609, 7979165, 8145857, 8152049, 10507438, 15017403, 29222367, 46505314, 48413717, 49857358, 50112675, 51014447, 57321670, 81065519, 103385283, 104302894, 118838433, 124893307, 125363753, 126651887, 128307820, 131499045, 134338084, 134989789, 135590731, 136986714, 137008459, 139078461, 143459061, 143799467, 144205979, 144207364, 151992462, 160841876, 160963576, 162129908, 162303127, 162789551, 163406911, 164809625, 165235538, 176321093, 178103750, 179116667, 184554139
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ChEBI ID |
CHEBI:4792
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ADReCS Drug ID | BADD_D00770 | |||
SuperDrug ATC ID |
N01AB04
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SuperDrug CAS ID |
cas=013838169
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Target and Pathway | Top | |||
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Target(s) | Glutamate receptor AMPA (GRIA) | Target Info | Suppressor | [3] |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7175). | |||
REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 074396. | |||
REF 3 | Enflurane directly depresses glutamate AMPA and NMDA currents in mouse spinal cord motor neurons independent of actions on GABAA or glycine receptors. Anesthesiology. 2000 Oct;93(4):1075-84. |
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