Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0A9PS
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| Former ID |
DNC000210
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| Drug Name |
Anandamide
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| Synonyms |
Anandamide; Arachidonylethanolamide; Arachidonoyl ethanolamide; N-Arachidonoylethanolamine; Anandamide (20.4, n-6); N-Arachidonoyl-2-hydroxyethylamide; 94421-68-8; AEA; N-arachidonoyl ethanolamine; N-(2-Hydroxyethyl)anachidonamide; 5,8,11,14-Eicosatetraenoylethanolamide; arachidonoylethanolamide; (5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-tetraenamide; Arachidonoyl-EA; UNII-UR5G69TJKH; Arachidonic acid N-(hydroxyethyl)amide; Anandamide(20:4, n-6); Anandamide (20:4, n-6)
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C22H37NO2
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| Canonical SMILES |
CCCCCC=CCC=CCC=CCC=CCCCC(=O)NCCO
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| InChI |
1S/C22H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)23-20-21-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-21H2,1H3,(H,23,25)/b7-6-,10-9-,13-12-,16-15-
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| InChIKey |
LGEQQWMQCRIYKG-DOFZRALJSA-N
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| CAS Number |
CAS 94421-68-8
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| PubChem Compound ID | ||||
| PubChem Substance ID |
13860, 841250, 4266218, 7978708, 8616858, 10587964, 11534104, 12014921, 14900691, 24890438, 26754689, 26754690, 26754691, 26754692, 26758228, 39315536, 47588771, 47736226, 47885183, 49681166, 49846802, 49964830, 50091575, 50110763, 53788936, 56365469, 57358469, 57389789, 71821418, 76140856, 81054506, 85208952, 85788018, 91702793, 92309949, 99300862, 99302381, 103178779, 104046462, 113856279, 124976956, 126524997, 127331025, 127331026, 127331027, 134339707, 135061638, 135651438, 137002864, 140063420
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| ChEBI ID |
CHEBI:2700
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cannabinoid receptor 1 (CB1) | Target Info | Agonist | [2] |
| KEGG Pathway | Rap1 signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Retrograde endocannabinoid signaling | ||||
| Panther Pathway | Endogenous cannabinoid signaling | |||
| Pathway Interaction Database | N-cadherin signaling events | |||
| Reactome | Class A/1 (Rhodopsin-like receptors) | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Small Ligand GPCRs | ||||
| BDNF signaling pathway | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2364). | |||
| REF 2 | Opioid receptor and NO/cGMP pathway as a mechanism of peripheral antinociceptive action of the cannabinoid receptor agonist anandamide. Life Sci. 2009 Aug 26;85(9-10):351-6. | |||
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