Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0A7ZH
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| Former ID |
DNC003381
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| Drug Name |
N-(2,3-DIFLUORO-BENZYL)-4-SULFAMOYL-BENZAMIDE
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| Synonyms |
N-(2,3-DIFLUORO-BENZYL)-4-SULFAMOYL-BENZAMIDE; N-[(2,3-difluorophenyl)methyl]-4-sulfamoylbenzamide; F2B; N-(2,3-Difluorobenzyl)-4-sulfamoylbenzamide; 235088-49-0; 2,3-difluoro-SBB; AC1L1C1I; CTK0I7898; BDBM12016; DTXSID80274323; 1g52; 1g46; AKOS030577745; DB07742; Benzamide, 4-(aminosulfonyl)-N-[(2,3-difluorophenyl)methyl]-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C14H12F2N2O3S
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| Canonical SMILES |
C1=CC(=C(C(=C1)F)F)CNC(=O)C2=CC=C(C=C2)S(=O)(=O)N
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| InChI |
1S/C14H12F2N2O3S/c15-12-3-1-2-10(13(12)16)8-18-14(19)9-4-6-11(7-5-9)22(17,20)21/h1-7H,8H2,(H,18,19)(H2,17,20,21)
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| InChIKey |
QASSMVGOSBNFQY-UHFFFAOYSA-N
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| CAS Number |
CAS 235088-49-0
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Carbonic anhydrase II (CA-II) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Nitrogen metabolism | |||
| Proximal tubule bicarbonate reclamation | ||||
| Collecting duct acid secretion | ||||
| Gastric acid secretion | ||||
| Pancreatic secretion | ||||
| Bile secretion | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| EGFR1 Signaling Pathway | ||||
| Reactome | Erythrocytes take up carbon dioxide and release oxygen | |||
| Erythrocytes take up oxygen and release carbon dioxide | ||||
| Reversible hydration of carbon dioxide | ||||
| WikiPathways | Reversible Hydration of Carbon Dioxide | |||
| Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | ||||
| Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. | |||
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