Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0A5EN
|
|||
| Former ID |
DCL000694
|
|||
| Drug Name |
AMG-714
|
|||
| Drug Type |
Antibody
|
|||
| Indication | Coeliac disease [ICD-11: DA95; ICD-10: K90.0; ICD-9: 579] | Phase 2 | [1] | |
| Rheumatoid arthritis [ICD-11: FA20] | Discontinued in Phase 1 | [2] | ||
| Company |
Genmab; Amgen
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Interleukin-15 (IL15) | Target Info | . | [2] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| Jak-STAT signaling pathway | ||||
| TNF signaling pathway | ||||
| Intestinal immune network for IgA production | ||||
| HTLV-I infection | ||||
| Herpes simplex infection | ||||
| Rheumatoid arthritis | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| FSH Signaling Pathway | ||||
| Leptin Signaling Pathway | ||||
| Panther Pathway | Interleukin signaling pathway | |||
| WikiPathways | Cytokines and Inflammatory Response | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
| REF 2 | Emerging drugs for rheumatoid arthritis. Expert Opin Emerg Drugs. 2008 Mar;13(1):175-96. | |||
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