Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0A4DR
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| Former ID |
DNC000184
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| Drug Name |
Alpha-methyl-alpha-phenylsuccinimide (MPS)
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| Synonyms |
2-Methyl-2-phenylsuccinimide; 1497-17-2; 3-methyl-3-phenylpyrrolidine-2,5-dione; alpha-Methyl-alpha-phenylsuccinimide; N-Desmethylmethsuximide; Normesuximide; 2,5-Pyrrolidinedione, 3-methyl-3-phenyl-; a-methyl-a-phenylsuccinimide; N-Demethylmethsuximide; UDESUGJZUFALAM-UHFFFAOYSA-N; 3-Methyl-3-phenyl-2,5-pyrrolidinedione; .alpha.-Methyl-.alpha.-phenylsuccinimide; Normethsuximide; N-Normethsuximide; Desmethylmethsuximide; EINECS 216-091-7; Mesuximide, M(nor-); AC1Q6LV6; AC1L3NJ7; SCHEMBL1568276; UDESUGJZUFALAM-UHFFFAOYSA-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C11H11NO2
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| Canonical SMILES |
CC1(CC(=O)NC1=O)C2=CC=CC=C2
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| InChI |
1S/C11H11NO2/c1-11(7-9(13)12-10(11)14)8-5-3-2-4-6-8/h2-6H,7H2,1H3,(H,12,13,14)
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| InChIKey |
UDESUGJZUFALAM-UHFFFAOYSA-N
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| CAS Number |
CAS 1497-17-2
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| PubChem Compound ID | ||||
| PubChem Substance ID |
3139785, 5523075, 10225220, 10508657, 15487500, 24888515, 44423020, 50895990, 57335144, 57756349, 89376265, 103811202, 104406672, 114917450, 117600755, 118740850, 126428116, 129351640, 131544229, 135048809, 135367264, 142322690, 143904767, 162232356, 164763688, 170153068, 172912813, 176237859, 184571982, 184828065, 204408181, 223251956, 223972182, 227764513, 249991549, 252128891, 252261785, 252345033
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated calcium channel alpha Cav3.1 (CACNA1G) | Target Info | Blocker | [1] |
| KEGG Pathway | MAPK signaling pathway | |||
| Calcium signaling pathway | ||||
| Circadian entrainment | ||||
| Type II diabetes mellitus | ||||
| Panther Pathway | Endogenous cannabinoid signaling | |||
| GABA-B receptor II signaling | ||||
| Nicotine pharmacodynamics pathway | ||||
| Pathwhiz Pathway | Muscle/Heart Contraction | |||
| Pathway Interaction Database | Regulation of nuclear beta catenin signaling and target gene transcription | |||
| Reactome | NCAM1 interactions | |||
| WikiPathways | NCAM signaling for neurite out-growth | |||
| Nicotine Activity on Chromaffin Cells | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Block of cloned human T-type calcium channels by succinimide antiepileptic drugs. Mol Pharmacol. 2001 Nov;60(5):1121-32. | |||
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