Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0A3ZU
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| Former ID |
DNCL002065
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| Drug Name |
Pomalidomide
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| Synonyms |
Actimid (TN); Pomalidomide (Immunomodulator)
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| Drug Type |
Small molecular drug
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| Indication | Systemic sclerosis [ICD-11: 4A42; ICD-9: 710.1] | Approved | [1], [2], [3] | |
| Company |
Celgene
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| Structure |
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Download2D MOL |
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| Formula |
C13H11N3O4
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| Canonical SMILES |
C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)N
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| InChI |
1S/C13H11N3O4/c14-7-3-1-2-6-10(7)13(20)16(12(6)19)8-4-5-9(17)15-11(8)18/h1-3,8H,4-5,14H2,(H,15,17,18)
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| InChIKey |
UVSMNLNDYGZFPF-UHFFFAOYSA-N
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| CAS Number |
CAS 19171-19-8
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| PubChem Compound ID | ||||
| PubChem Substance ID |
10243744, 14848461, 29312424, 50086901, 50447747, 53787052, 57345004, 96025659, 103100612, 103221733, 104253216, 104382952, 117621779, 124757341, 125164145, 125697093, 129427476, 135089995, 135727444, 136348254, 136367549, 136946644, 137009922, 142523166, 143499180, 149539643, 152235120, 152258286, 152343904, 160647125, 160837107, 162011791, 162012270, 162037668, 162189531, 162856472, 163398415, 163778934, 163907985, 164194051, 172889447, 172889448, 173130995, 174007398, 174528127, 175424471, 175427148, 178103920, 179116970, 186007045
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| ChEBI ID |
CHEBI:72690
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| ADReCS Drug ID | BADD_D01798 | |||
| SuperDrug ATC ID |
L04AX06
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| Drug Resistance Mutation (DRM) | Top | |||
|---|---|---|---|---|
| DRM | DRM Info | |||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Angiogenesis/myeloma cell growth (AMCG) | Target Info | Modulator | [2], [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7348). | |||
| REF 2 | Radium 223 dichloride for prostate cancer treatment. Drug Des Devel Ther. 2017 Sep 6;11:2643-2651. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
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