Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0A0YZ
|
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| Former ID |
DNC002409
|
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| Drug Name |
PYZD-4409
|
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| Drug Type |
Small molecular drug
|
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| Indication | leukaemia [ICD-11: 2A60-2B33; ICD-9: 208.9] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C14H7ClFN3O5
|
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| Canonical SMILES |
C1=CC(=C(C=C1N2C(=O)C(=CC3=CC=C(O3)[N+](=O)[O-])C(=O)N2)Cl)F
|
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| InChI |
1S/C14H7ClFN3O5/c15-10-5-7(1-3-11(10)16)18-14(21)9(13(20)17-18)6-8-2-4-12(24-8)19(22)23/h1-6H,(H,17,20)/b9-6-
|
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| InChIKey |
MSYMKEYWUWVZQY-TWGQIWQCSA-N
|
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| CAS Number |
CAS 423148-78-1
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Ubiquitin-activating enzyme E1 (UBAE1) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma. Blood. 2010 Mar 18;115(11):2251-9. | |||
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