Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0A0RM
|
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| Drug Name |
PMID26815044-Compound-51
|
|||
| Drug Type |
Small molecular drug
|
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| Indication | Albinism [ICD-11: EC23.2; ICD-10: E70.3, H90.3] | Patented | [1] | |
| Ephelides [ICD-11: ED61.0] | Patented | [1] | ||
| Melasma [ICD-11: ED60.1] | Patented | [1] | ||
| Menkes disease [ICD-11: 5C64.0; ICD-10: E83.0] | Patented | [1] | ||
| Senile lentigines [ICD-11: ED61.0] | Patented | [1] | ||
| Company |
Boiteau J-G, Barbuis CM, Talano S
|
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| Structure |
 |
Download2D MOL |
||
| Formula |
C10H8F2N2OS
|
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| Canonical SMILES |
C1=CC(=CC=C1C2=CNC(=S)N2)OC(F)F
|
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| InChI |
1S/C10H8F2N2OS/c11-9(12)15-7-3-1-6(2-4-7)8-5-13-10(16)14-8/h1-5,9H,(H2,13,14,16)
|
|||
| InChIKey |
RSUPNTVGCZRJCF-UHFFFAOYSA-N
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Tyrosinase (TYR) | Target's Patent Info | [1] | |
| BioCyc | (S)-reticuline biosynthesis | |||
| Eumelanin biosynthesis | ||||
| L-dopachrome biosynthesis | ||||
| KEGG Pathway | Tyrosine metabolism | |||
| Riboflavin metabolism | ||||
| Metabolic pathways | ||||
| Melanogenesis | ||||
| Pathwhiz Pathway | Riboflavin Metabolism | |||
| Tyrosine Metabolism | ||||
| WikiPathways | Dopamine metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Tyrosinase inhibitors: a patent review (2011-2015).Expert Opin Ther Pat. 2016;26(3):347-62. | |||
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