Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09ZIC
|
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| Former ID |
DNC001015
|
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| Drug Name |
N-hydroxy-nor-L-arginine
|
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| Structure |
 |
Download2D MOL |
||
| Formula |
C5H12N4O3
|
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| Canonical SMILES |
C(CN=C(N)NO)C(C(=O)O)N
|
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| InChI |
1S/C5H12N4O3/c6-3(4(10)11)1-2-8-5(7)9-12/h3,12H,1-2,6H2,(H,10,11)(H3,7,8,9)/t3-/m0/s1
|
|||
| InChIKey |
KOBHCUDVWOTEKO-VKHMYHEASA-N
|
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| CAS Number |
CAS 189302-40-7
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Kidney-type arginase (ARG2) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Arginine and proline metabolism | |||
| Metabolic pathways | ||||
| Biosynthesis of antibiotics | ||||
| Biosynthesis of amino acids | ||||
| Amoebiasis | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| WikiPathways | Urea cycle and metabolism of amino groups | |||
| Metabolism of amino acids and derivatives | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Arginase reciprocally regulates nitric oxide synthase activity and contributes to endothelial dysfunction in aging blood vessels. Circulation. 2003 Oct 21;108(16):2000-6. | |||
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