Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D09YVX
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| Former ID |
DIB004731
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| Drug Name |
Etofenamate
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| Synonyms |
ETOFENAMATE; 30544-47-9; Rheumon; Bayrogel; Rheumon gel; UNII-KZF0XM66JC; Etofenamatum [INN-Latin]; Etofenamato [INN-Spanish]; Bay d 1107; C18H18F3NO4; TVX 485; WHR 5020; EINECS 250-231-8; KZF0XM66JC; BRN 2953263; 2-(2-Hydroxyethoxy)ethyl 2-((3-(trifluoromethyl)phenyl)amino)benzoate; 2-(2-hydroxyethoxy)ethyl 2-[3-(trifluoromethyl)anilino]benzoate; WHR-5020; NCGC00016804-01; 2-(2-Hydroxyaethoxy)aethylester der flutenaminsaeure [German]; CAS-30544-47-9; 2-(2-hydroxyethoxy)ethyl 2-{[3-(trifluoromethyl)phenyl]amino}benzoate
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| Drug Type |
Small molecular drug
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| Indication | Rheumatoid arthritis [ICD-11: FA20] | Approved | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C18H18F3NO4
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| Canonical SMILES |
C1=CC=C(C(=C1)C(=O)OCCOCCO)NC2=CC=CC(=C2)C(F)(F)F
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| InChI |
1S/C18H18F3NO4/c19-18(20,21)13-4-3-5-14(12-13)22-16-7-2-1-6-15(16)17(24)26-11-10-25-9-8-23/h1-7,12,22-23H,8-11H2
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| InChIKey |
XILVEPYQJIOVNB-UHFFFAOYSA-N
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| CAS Number |
CAS 30544-47-9
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:94731
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| Interaction between the Drug and Microbe | Top | |||
|---|---|---|---|---|
| The Abundace of Studied Microbe(s) Regulated by Drug | ||||
| The Order in the Taxonomic Hierarchy of the following Microbe(s): Bacteroidales | ||||
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Studied Microbe: Bacteroides ovatus
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[2] | |||
| Hierarchy | ||||
| Abundance Change | Decrease | |||
| Experiment Method | High-throughput screening | |||
| Description | The abundance of Bacteroides ovatus was decreased by Etofenamate (adjusted p-values: 3.05E-04). | |||
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Studied Microbe: Parabacteroides distasonis
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[2] | |||
| Hierarchy | ||||
| Abundance Change | Decrease | |||
| Experiment Method | High-throughput screening | |||
| Description | The abundance of Parabacteroides distasonis was decreased by Etofenamate (adjusted p-values: 3.39E-04). | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | Extensive impact of non-antibiotic drugs on human gut bacteria. Nature. 2018 Mar 29;555(7698):623-628. | |||
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