Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09VFU
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| Former ID |
DIB001428
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| Drug Name |
MST-400
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| Synonyms |
MST-400 series; MST-500 series; Integrin-linked kinase inhibitors (cancer); Integrin-linked kinase inhibitors (cancer), MetaSignal
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Investigative | [1] | |
| Company |
MetaSignal Therapeutics
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Integrin-linked protein kinase 1 (ILK) | Target Info | Inhibitor | [1] |
| NetPath Pathway | TCR Signaling Pathway | |||
| FSH Signaling Pathway | ||||
| Panther Pathway | Integrin signalling pathway | |||
| Pathway Interaction Database | Osteopontin-mediated events | |||
| Integrin-linked kinase signaling | ||||
| Integrins in angiogenesis | ||||
| Reactome | Localization of the PINCH-ILK-PARVIN complex to focal adhesions | |||
| WikiPathways | Eukaryotic Transcription Initiation | |||
| Focal Adhesion | ||||
| Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| Integrin-mediated Cell Adhesion | ||||
| Cell junction organization | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2041). | |||
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