Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09VAZ
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| Former ID |
DNC011083
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| Drug Name |
TRIENTINE
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| Synonyms |
Trientine HCl; 21121-06-2; triethylenetetramine HCl; SMR000058543; AC1NUQ0M; MLS000069683; SCHEMBL205201; CHEMBL1200783; CTK0I9735; DTXSID80419994; XPVOJYDIBHYVFL-UHFFFAOYSA-N; Pharmakon1600-01505675; NSC759164; NSC158271; AKOS027276425; NSC-158271; NSC-759164; 1, N,N'-bis(2-aminoethyl)-, tetrahydrochloride; 1,2-Ethanediamine, N,N'-bis(2-aminoethyl)-, hydrochloride; N'-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine hydrochloride
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| Drug Type |
Small molecular drug
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| Indication | Inborn error of metabolism [ICD-11: 5C50-5C59] | Approved | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C6H18N4
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| Canonical SMILES |
C(CNCCNCCN)N
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| InChI |
1S/C6H18N4/c7-1-3-9-5-6-10-4-2-8/h9-10H,1-8H2
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| InChIKey |
VILCJCGEZXAXTO-UHFFFAOYSA-N
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| CAS Number |
CAS 112-24-3
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:39501
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| ADReCS Drug ID | BADD_D02279 | |||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Carbonic anhydrase XIV (CA-XIV) | Target Info | Inhibitor | [2] |
| KEGG Pathway | Nitrogen metabolism | |||
| Reactome | Reversible hydration of carbon dioxide | |||
| WikiPathways | Reversible Hydration of Carbon Dioxide | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule. J Med Chem. 2010 Aug 12;53(15):5511-22. | |||
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