Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D09TPF
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| Former ID |
DAP000979
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| Drug Name |
Molindone
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| Synonyms |
Molindona; Molindonum; Molindone Monohydrochloride; Molindona [INN-Spanish]; Molindone (INN); Molindone (MOL); Molindone [INN:BAN]; Molindonum [INN-Latin]; (+-)-Molindone; 3-Ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-4H-indol-4-one; 3-Ethyl-6,7-dihydro-2-methyl-5-(morpholinomethyl)indol-4(5H)-one; 3-ethyl-2-methyl-5-(morpholin-4-ylmethyl)-1,5,6,7-tetrahydro-4H-indol-4-one; 3-ethyl-2-methyl-5-(morpholin-4-ylmethyl)-1,5,6,7-tetrahydroindol-4-one; 3-ethyl-2-methyl-5-(morpholin-4-ylmethyl)-4,5,6,7-tetrahydro-1H-indol-4-one
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| Drug Type |
Small molecular drug
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| Indication | Schizophrenia [ICD-11: 6A20] | Approved | [1], [2] | |
| Therapeutic Class |
Antipsychotic Agents
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| Structure |
 |
Download2D MOL |
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| Formula |
C16H24N2O2
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| Canonical SMILES |
CCC1=C(NC2=C1C(=O)C(CC2)CN3CCOCC3)C
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| InChI |
1S/C16H24N2O2/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18/h12,17H,3-10H2,1-2H3
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| InChIKey |
KLPWJLBORRMFGK-UHFFFAOYSA-N
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| CAS Number |
CAS 7416-34-4
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9439, 7784248, 8167438, 10534390, 11467063, 11468183, 11486836, 14799490, 26755691, 29291008, 46504744, 47320783, 47320784, 48289519, 48289520, 48365147, 48416291, 49699386, 49984921, 50111112, 50836898, 57331496, 85209915, 85787545, 90341242, 92723324, 96024914, 99375691, 103167157, 104021724, 104179135, 104359414, 117423090, 117597268, 125562976, 126626997, 126652518, 126663373, 128400085, 131377755, 134223702, 134338250, 134987862, 135650621, 135874693, 137260961, 140261912, 143493298, 152038486, 152235779
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| ChEBI ID |
CHEBI:6965
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| ADReCS Drug ID | BADD_D01487 | |||
| SuperDrug ATC ID |
N05AE02
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| SuperDrug CAS ID |
cas=007416344
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 207). | |||
| REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 017111. | |||
| REF 3 | Molindone for schizophrenia and severe mental illness. Cochrane Database Syst Rev. 2007 Jan 24;(1):CD002083. | |||
| REF 4 | Antipsychotic drugs which elicit little or no parkinsonism bind more loosely than dopamine to brain D2 receptors, yet occupy high levels of these receptors. Mol Psychiatry. 1998 Mar;3(2):123-34. | |||
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