Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09TLE
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| Former ID |
DIB006350
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| Drug Name |
Tefinostat
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| Synonyms |
CHR-2845; CHR-2847; CHR-2875; Small molecule inhibitor (hematological malignancies), Chroma
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| Drug Type |
Small molecular drug
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Phase 1 | [1] | |
| Company |
Chroma Therapeutics Ltd
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| Structure |
 |
Download2D MOL |
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| Formula |
C28H37N3O5
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| Canonical SMILES |
C1CCC(C1)OC(=O)C(C2=CC=CC=C2)NCC3=CC=C(C=C3)NC(=O)CCCCCCC(=O)NO
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| InChI |
1S/C28H37N3O5/c32-25(14-6-1-2-7-15-26(33)31-35)30-23-18-16-21(17-19-23)20-29-27(22-10-4-3-5-11-22)28(34)36-24-12-8-9-13-24/h3-5,10-11,16-19,24,27,29,35H,1-2,6-9,12-15,20H2,(H,30,32)(H,31,33)/t27-/m0/s1
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| InChIKey |
GLNWREBYRLDPQP-MHZLTWQESA-N
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| CAS Number |
CAS 914382-60-8
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00820508) Safety and Tolerability of CHR-2845 to Treat Haematological Diseases or Lymphoid Malignancies. U.S. National Institutes of Health. | |||
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