Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09TFL
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| Former ID |
DNCL002672
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| Drug Name |
PCI-27483
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| Indication | Pancreatic cancer [ICD-11: 2C10; ICD-9: 185] | Phase 2 | [1] | |
| Company |
Pharmacyclics Sunnyvale, CA
|
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| Structure |
 |
Download2D MOL |
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| Formula |
C26H24N6O9S
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| Canonical SMILES |
C1=CC2=C(C=C1C(=N)N)NC(=N2)C3=CC(=CC(=C3O)C4=C(C=CC(=C4)S(=O)(=O)N)O)CC(=O)NC(CC(=O)O)C(=O)O
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| InChI |
1S/C26H24N6O9S/c27-24(28)12-1-3-17-18(8-12)32-25(31-17)16-6-11(7-21(34)30-19(26(38)39)10-22(35)36)5-15(23(16)37)14-9-13(42(29,40)41)2-4-20(14)33/h1-6,8-9,19,33,37H,7,10H2,(H3,27,28)(H,30,34)(H,31,32)(H,35,36)(H,38,39)(H2,29,40,41)/t19-/m0/s1
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| InChIKey |
WDJHHCAKBRKCLW-IBGZPJMESA-N
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| CAS Number |
CAS 871266-63-6
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01020006) Study of Safety and Tolerability of PCI-27483 in Patients With Pancreatic Cancer Patients Receiving Treatment With Gemcitabine. U.S. National Institutes of Health. | |||
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