Drug Information
Drug General Information | Top | |||
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Drug ID |
D09TBD
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Former ID |
DAP001203
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Drug Name |
Sulfisoxazole
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Synonyms |
Accuzole; Alphazole; Amidoxal; Astrazolo; Azosulfizin; Bactesulf; Barazae; Chemouag; Cosoxazole; Dorsulfan; ERYZOLE; Entusil; Entusul; Ganda; Gantrisin; Gantrisine; Gantrisona; Gantrosan; Isoxamin; Neazolin; Neoxazoi; Neoxazol; Novazolo; Novosaxazole; Pancid; Renosulfan; Resoxol; Roxosul; Roxoxol; SOXO; Saxosozine; Sodizole; Solfafurazolo; Sosol; Soxamide; Soxazole; Soxisol; Soxitabs; Soxomide; Stansin; Sulbio; Sulfadimethylisoxazole; Sulfafurazol; Sulfafurazole; Sulfafurazolum; Sulfagan; Sulfagen; Sulfaisoxazole; Sulfalar; Sulfapolar; Sulfasol; Sulfasoxazole; Sulfasoxizole; Sulfazin; Sulfisin; Sulfisonazole; Sulfisoxasole; Sulfisoxazol; Sulfisoxazolum; Sulfizin; Sulfizol; Sulfizole; Sulfofurazole; Sulfoxol; Suloxsol; Sulphadimethylisoxazole; Sulphafuraz; Sulphafurazol; Sulphafurazole; Sulphafurazolum; Sulphaisoxazole; Sulphisoxazol; Sulphisoxazole; Sulphofurazole; Sulsoxin; Thiasin; Unisulf; Urisoxin; Uritrisin; Urogan; Vagilia; Azo Gantrisin; Component of Azo Gantrisin; Component of Azo Gantrisin Accuzole; Dorsulfan warthausen; Roxosul tablets; Solfafurazolo [DCIT]; Sulfafuraz ole; Sulfisoxazole [USAN]; Sulfisoxazole dialamine; NU 445; Component of Azo-Sulfizin; G-sox; Gantrisin (TN); J-Sul; Koro-sulf; Norilgan-S; SK-Soxazole; Sulfafurazole (INN); Sulfafurazolum [INN-Latin]; Sulfazin (VAN); Sulfisoxazole-Carc; Tl-azole; US-67; V-Sul; Sulfisoxazole (JP15/USP); U.S.-67; 3,4-Dimethyl-5-sulfanilamidoisoxazole; 3,4-Dimethyl-5-sulfonamidoisoxazole; 3,4-Dimethyl-5-sulphanilamidoisoxazole; 3,4-Dimethyl-5-sulphonamidoisoxazole; 3,4-Dimethylisoxale-5-sulfanilamide; 3,4-Dimethylisoxazole-5-sulfanilamide; 3,4-Dimethylisoxazole-5-sulphanilamide; 3,4-dimethylisoaxazole-5-sulfanilimide; 5-Sulfanilamido-3,4-dimethyl-isoxazole; 5-Sulfanilamido-3,4-dimethylisoxazole; 5-Sulphanilamido-3,4-dimethyl-isoxazole
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Drug Type |
Small molecular drug
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Indication | Urinary tract infection [ICD-11: GC08; ICD-10: N39] | Approved | [1] | |
Therapeutic Class |
Antiinfective Agents
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Company |
Hoffmann La Roche Inc
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Structure |
Download2D MOL |
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Formula |
C11H13N3O3S
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Canonical SMILES |
CC1=C(ON=C1C)NS(=O)(=O)C2=CC=C(C=C2)N
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InChI |
1S/C11H13N3O3S/c1-7-8(2)13-17-11(7)14-18(15,16)10-5-3-9(12)4-6-10/h3-6,14H,12H2,1-2H3
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InChIKey |
NHUHCSRWZMLRLA-UHFFFAOYSA-N
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CAS Number |
CAS 127-69-5
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PubChem Compound ID | ||||
PubChem Substance ID |
9526, 77649, 91794, 94502, 519811, 603111, 855841, 859862, 5632698, 7847516, 7980707, 8001163, 8149542, 8153283, 10321680, 10506243, 10589442, 11112277, 11113344, 11335754, 11360993, 11363918, 11366480, 11369042, 11372695, 11373896, 11377204, 11461965, 11466362, 11467482, 11485185, 11486024, 11489141, 11491543, 11492164, 11494838, 14848258, 17389726, 17390719, 24707909, 24899697, 26611934, 26679889, 26747009, 26751527, 29224396, 46505342, 47291108, 47440228, 47662260
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ChEBI ID |
CHEBI:102484
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SuperDrug ATC ID |
J01EB05; S01AB02
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SuperDrug CAS ID |
cas=000127695
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Target and Pathway | Top | |||
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Target(s) | Bacterial Dihydropteroate synthetase (Bact folP) | Target Info | Inhibitor | [2] |
References | Top | |||
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REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
REF 2 | Inhibition of recombinant Pneumocystis carinii dihydropteroate synthetase by sulfa drugs. Antimicrob Agents Chemother. 1995 Aug;39(8):1756-63. |
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