Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09QUQ
|
|||
| Former ID |
DAP001233
|
|||
| Drug Name |
Levobupivacaine
|
|||
| Synonyms |
Novabupi; Chirocaine (TN); Levobupivacaine (INN); Levobupivacaine [INN:BAN]; Novabupi (TN); L(-)-Bupivacaine; L-(-)-bupivacaine; L-(-)-1-Butyl-2',6'-pipecoloxylidide; (2S)-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide; (S)-1-Butyl-2',6'-pipecoloxylidide; (S)-bupivacaine
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Anaesthesia [ICD-11: 9A78.6; ICD-9: 338] | Approved | [1], [2] | |
| Therapeutic Class |
Anesthetics
|
|||
| Company |
AstraZeneca
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C18H28N2O
|
|||
| Canonical SMILES |
CCCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C
|
|||
| InChI |
1S/C18H28N2O/c1-4-5-12-20-13-7-6-11-16(20)18(21)19-17-14(2)9-8-10-15(17)3/h8-10,16H,4-7,11-13H2,1-3H3,(H,19,21)/t16-/m0/s1
|
|||
| InChIKey |
LEBVLXFERQHONN-INIZCTEOSA-N
|
|||
| CAS Number |
CAS 27262-47-1
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID |
10089, 10225294, 11112642, 14775644, 14800000, 29215441, 44423110, 46505295, 50010834, 50070564, 50071325, 57335205, 80394341, 93166629, 96024806, 104222110, 104406939, 123092444, 126592946, 126669543, 126669544, 128475942, 131308447, 134338472, 135048182, 136357477, 137248692, 160964338, 162174730, 163366975, 175271332, 178103786, 179150260, 185974045, 187072685, 198980870, 218903197, 223535869, 223666603, 223666604, 223850360, 226420984, 251916836, 251918075, 252451169
|
|||
| ChEBI ID |
CHEBI:6149
|
|||
| ADReCS Drug ID | BADD_D01269 | |||
| SuperDrug ATC ID |
N01BB10
|
|||
| SuperDrug CAS ID |
cas=027262471
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sodium channel unspecific (NaC) | Target Info | Blocker | [3] |
| KEGG Pathway | Dopaminergic synapse | |||
| Reactome | Interaction between L1 and Ankyrins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7211). | |||
| REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 020997. | |||
| REF 3 | Block of neuronal tetrodotoxin-resistant Na+ currents by stereoisomers of piperidine local anesthetics. Anesth Analg. 2000 Dec;91(6):1499-505. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.