Drug Information
Drug General Information | Top | |||
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Drug ID |
D09POE
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Former ID |
DNC000979
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Drug Name |
N-(6)-methyl-2'-deoxyadenosine-3',5'-bisphosphate
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] |
Target and Pathway | Top | |||
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Target(s) | P2Y purinoceptor 1 (P2RY1) | Target Info | Antagonist | [1] |
KEGG Pathway | Rap1 signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Platelet activation | ||||
Reactome | G alpha (q) signalling events | |||
P2Y receptors | ||||
ADP signalling through P2Y purinoceptor 1 | ||||
WikiPathways | Nucleotide GPCRs | |||
GPCRs, Class A Rhodopsin-like | ||||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
Signal amplification | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | Key role of the P2Y(1) receptor in tissue factor-induced thrombin-dependent acute thromboembolism: studies in P2Y(1)-knockout mice and mice treated with a P2Y(1) antagonist. Circulation. 2001 Feb 6;103(5):718-23. |
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