Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09PLZ
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| Former ID |
DIB001523
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| Drug Name |
NI-1201
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| Synonyms |
Anti-interleukin-6 receptor mAb, NovImmune
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| Drug Type |
Antibody
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| Indication | Autoimmune diabetes [ICD-11: 5A10] | Investigative | [1] | |
| Company |
NovImmune SA
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Interleukin 6 receptor (IL6R) | Target Info | . | [1] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| HIF-1 signaling pathway | ||||
| PI3K-Akt signaling pathway | ||||
| Jak-STAT signaling pathway | ||||
| Hematopoietic cell lineage | ||||
| Non-alcoholic fatty liver disease (NAFLD) | ||||
| Reactome | MAPK3 (ERK1) activation | |||
| MAPK1 (ERK2) activation | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Senescence and Autophagy in Cancer | ||||
| IL-6 signaling pathway | ||||
| Differentiation Pathway | ||||
| Interleukin-6 signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2310). | |||
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