Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D09PGM
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| Former ID |
DIB014704
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| Drug Name |
BY-1949
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| Synonyms |
BY-1949; 90158-59-1; 3-Methoxy-11-methyldibenz(b,f)oxazepine-8-carboxylate; AC1L3SM5; SCHEMBL194184; DTXSID60238049; JTZGDJSJVQONAV-UHFFFAOYSA-N; 11-methyl-3-methoxydibenz[b,f][1,4]oxazepine-8-carboxylic acid; Dibenz(b,f)(1,4)oxazepine-8-carboxylic acid, 3-methoxy-11-methyl-; 9-methoxy-6-methylbenzo[b][1,4]benzoxazepine-3-carboxylic acid; 3-methoxy-11-methyldibenzo[b,f][1,4]oxazepin-8-carboxylic acid
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| Drug Type |
Small molecular drug
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| Indication | Cognitive impairment [ICD-11: 6D71; ICD-10: F06.7] | Discontinued in Phase 2 | [1] | |
| Company |
Chugai Pharmaceutical Co Ltd
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| Structure |
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Download2D MOL |
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| Formula |
C16H13NO4
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| Canonical SMILES |
CC1=NC2=C(C=CC(=C2)C(=O)O)OC3=C1C=CC(=C3)OC
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| InChI |
1S/C16H13NO4/c1-9-12-5-4-11(20-2)8-15(12)21-14-6-3-10(16(18)19)7-13(14)17-9/h3-8H,1-2H3,(H,18,19)
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| InChIKey |
JTZGDJSJVQONAV-UHFFFAOYSA-N
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| CAS Number |
CAS 90158-59-1
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | ATP phosphatase (ATPase) | Target Info | Modulator | [2] |
| References | Top | |||
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| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001319) | |||
| REF 2 | An activation of synaptosomal Na+,K(+)-ATPase by a novel dibenzoxazepine derivative (BY-1949) in the rat brain: its functional role in the neurotransmitter uptake systems. J Neurochem. 1992 Jan;58(1):362-8. | |||
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