Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09OZC
|
|||
| Former ID |
DAP001003
|
|||
| Drug Name |
Lucanthone
|
|||
| Synonyms |
Lucanthon; Lucanthonum; Lucantona; Miracol; Nilodin; Scapuren; Tixantone; LUCANTHONE HYDROCHLORIDE; Lucanthone monohydrochloride; Miracil D; BW 57223; CBC 900139; DR-15771; Lucanthone [INN:BAN]; Lucanthonum [INN-Latin]; Lucantona [INN-Spanish]; 1-((2-(Diethylamino)ethyl)amino)-4-methylthioxanthen-9-one; 1-(2-diethylaminoethylamino)-4-methylthioxanthen-9-one; 1-[[2-(Diethylamino)ethyl]amino]-4-methylthioxanthone; 1-{[2-(Diethylamino)ethyl]amino}-4-methyl-9H-thioxanthen-9-one; 9H-Thioxanthen-9-one, 1-((2-(diethylamino)ethyl)amino)-4-methyl-(9CI)
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Approved | [1] | |
| Therapeutic Class |
Anticancer Agents
|
|||
| Company |
Spectrum
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C20H24N2OS
|
|||
| Canonical SMILES |
CCN(CC)CCNC1=C2C(=C(C=C1)C)SC3=CC=CC=C3C2=O
|
|||
| InChI |
1S/C20H24N2OS/c1-4-22(5-2)13-12-21-16-11-10-14(3)20-18(16)19(23)15-8-6-7-9-17(15)24-20/h6-11,21H,4-5,12-13H2,1-3H3
|
|||
| InChIKey |
FBQPGGIHOFZRGH-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 479-50-5
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID |
13880, 605885, 6717762, 8157342, 11405383, 11447473, 15422229, 29228710, 46507260, 48416189, 50054621, 56394814, 57326018, 76348844, 103188497, 104322601, 124633672, 125824256, 126671567, 127823040, 134223140, 134338273, 134974173, 137005643, 142383948, 160967835, 179150492, 184531387, 198952423, 223670988, 226400151, 252215717
|
|||
| ChEBI ID |
CHEBI:51052
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | DNA topoisomerase II (TOP2) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drug information of Lucanthone, 2008. eduDrugs. | |||
| REF 2 | Clonogenicity of human leukemic cells protected from cell-lethal agents by heat shock protein 70. Cell Stress Chaperones. 2005 Spring;10(1):37-45. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.