Drug Information
Drug General Information | Top | |||
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Drug ID |
D09OWC
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Former ID |
DIB002917
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Drug Name |
SKLB-010
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Synonyms |
Thiazolidinediones (inflammation), Sichuan University
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Indication | Inflammation [ICD-11: 1A00-CA43.1] | Investigative | [1] | |
Company |
Sichuan University
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Structure |
Download2D MOL |
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Formula |
C11H9NO3S
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Canonical SMILES |
COC1=CC=C(C=C1)C=C2C(=O)NC(=O)S2
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InChI |
1S/C11H9NO3S/c1-15-8-4-2-7(3-5-8)6-9-10(13)12-11(14)16-9/h2-6H,1H3,(H,12,13,14)/b9-6-
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InChIKey |
VRUKGUBMRBLJJW-TWGQIWQCSA-N
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CAS Number |
CAS 6320-51-0
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Nitric-oxide synthase inducible (NOS2) | Target Info | Modulator | [1] |
BioCyc | Citrulline-nitric oxide cycle | |||
KEGG Pathway | Arginine biosynthesis | |||
Arginine and proline metabolism | ||||
Metabolic pathways | ||||
Calcium signaling pathway | ||||
HIF-1 signaling pathway | ||||
Peroxisome | ||||
Salmonella infection | ||||
Pertussis | ||||
Leishmaniasis | ||||
Chagas disease (American trypanosomiasis) | ||||
Toxoplasmosis | ||||
Amoebiasis | ||||
Tuberculosis | ||||
Pathways in cancer | ||||
Small cell lung cancer | ||||
NetPath Pathway | IL1 Signaling Pathway | |||
IL2 Signaling Pathway | ||||
Pathway Interaction Database | IL12-mediated signaling events | |||
Alpha9 beta1 integrin signaling events | ||||
ATF-2 transcription factor network | ||||
IL23-mediated signaling events | ||||
Signaling mediated by p38-alpha and p38-beta | ||||
HIF-1-alpha transcription factor network | ||||
Reactome | ROS production in response to bacteria | |||
Nitric oxide stimulates guanylate cyclase | ||||
WikiPathways | Type II interferon signaling (IFNG) | |||
Spinal Cord Injury | ||||
AGE/RAGE pathway | ||||
Effects of Nitric Oxide |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1250). |
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