Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09NYB
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| Former ID |
DIB000712
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| Drug Name |
CASTANOSPERMINE
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| Synonyms |
MDL-26190; (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyoctahydroindolizine
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| Drug Type |
Small molecular drug
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| Indication | Diabetic complication [ICD-11: 5A2Y; ICD-9: 253.5, 588.1] | Discontinued in Phase 2 | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C8H15NO4
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| Canonical SMILES |
C1CN2CC(C(C(C2C1O)O)O)O
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| InChI |
1S/C8H15NO4/c10-4-1-2-9-3-5(11)7(12)8(13)6(4)9/h4-8,10-13H,1-3H2/t4-,5-,6+,7+,8+/m0/s1
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| InChIKey |
JDVVGAQPNNXQDW-TVNFTVLESA-N
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| CAS Number |
CAS 79831-76-8
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:27860
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glucosidase unspecific (GAN) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004537) | |||
| REF 2 | Castanospermine inhibits alpha-glucosidase activities and alters glycogen distribution in animals. Proc Natl Acad Sci U S A. 1985 Jan;82(1):93-7. | |||
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