Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D09KRH
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| Former ID |
DIB019775
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| Drug Name |
domoic acid
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| Synonyms |
domoate; NSC 288031
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C15H21NO6
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| Canonical SMILES |
CC(C=CC=C(C)C1CNC(C1CC(=O)O)C(=O)O)C(=O)O
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| InChI |
1S/C15H21NO6/c1-8(4-3-5-9(2)14(19)20)11-7-16-13(15(21)22)10(11)6-12(17)18/h3-5,9-11,13,16H,6-7H2,1-2H3,(H,17,18)(H,19,20)(H,21,22)/b5-3+,8-4-/t9-,10+,11-,13+/m1/s1
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| InChIKey |
VZFRNCSOCOPNDB-AOKDLOFSSA-N
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| CAS Number |
CAS 14277-97-5
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| PubChem Compound ID | ||||
| PubChem Substance ID |
586321, 7887137, 8616969, 14719311, 24894006, 26751666, 26758635, 39315722, 50038062, 57358598, 78284545, 85788985, 91696040, 113856771, 117682352, 123092445, 124812230, 134221965, 135057153, 137242511, 162022521, 163688206, 175607738, 176265315, 178101000, 179316856, 198954949, 223442148, 226717272, 241181599, 241376073, 250134635, 252553471
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| ChEBI ID |
CHEBI:34727
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glutamate receptor ionotropic kainate 1 (GRIK1) | Target Info | Agonist | [2] |
| Glutamate receptor ionotropic kainate 2 (GRIK2) | Target Info | Agonist | [3] | |
| Glutamate receptor ionotropic kainate 4 (GluK4) | Target Info | Agonist | [4] | |
| Glutamate receptor ionotropic kainate 5 (GRIK5) | Target Info | Agonist | [5] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Glutamatergic synapse | ||||
| Panther Pathway | Huntington disease | |||
| Ionotropic glutamate receptor pathway | ||||
| Metabotropic glutamate receptor group III pathway | ||||
| Metabotropic glutamate receptor group I pathway | ||||
| WikiPathways | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4181). | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 450). | |||
| REF 3 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 451). | |||
| REF 4 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 453). | |||
| REF 5 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 454). | |||
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