Drug Information
Drug General Information | Top | |||
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Drug ID |
D09INF
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Former ID |
DCL000860
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Drug Name |
Laquinamod
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Synonyms |
Laquinimod sodium; Laquinimod Sodium Salt; 248282-07-7; UNII-4H914M0CSP; Laquinimod sodium [USAN]; TV-5600; 4H914M0CSP; ABR-215062 SODIUM; Laquinimod sodium (USAN); sodium 5-chloro-3-(ethyl(phenyl)carbamoyl)-1-methyl-2-oxo-1,2-dihydroquinolin-4-olate; SAIK-MS compound; ABR 215062 Sodium; SCHEMBL1991182; CHEMBL2103814; DTXSID50179538; QCR-166; JWHPPWBIIQMBQC-UHFFFAOYSA-M; AKOS027326368; TV 5600; FT-0670730; D08938; Sodium 5-chloro-3-(ethylphenylcarbamoyl)-1-methyl-2-oxo-1,2-dihydroquinolin- 4-olate; 3-Quinolinecarboxamide, 5-chlo
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Drug Type |
Small molecular drug
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Indication | Multiple sclerosis [ICD-11: 8A40; ICD-9: 340] | Phase 3 | [1] | |
Company |
Active Biotech; Teva
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Structure |
Download2D MOL |
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Formula |
C19H16ClN2NaO3
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Canonical SMILES |
CCN(C1=CC=CC=C1)C(=O)C2=C(C3=C(C=CC=C3Cl)N(C2=O)C)[O-].[Na+]
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InChI |
1S/C19H17ClN2O3.Na/c1-3-22(12-8-5-4-6-9-12)19(25)16-17(23)15-13(20)10-7-11-14(15)21(2)18(16)24;/h4-11,23H,3H2,1-2H3;/q;+1/p-1
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InChIKey |
JWHPPWBIIQMBQC-UHFFFAOYSA-M
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CAS Number |
CAS 248282-07-7
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | C-X-C motif chemokine 2 (CXCL2) | Target Info | Modulator | [1] |
KEGG Pathway | Cytokine-cytokine receptor interaction | |||
Chemokine signaling pathway | ||||
NF-kappa B signaling pathway | ||||
NOD-like receptor signaling pathway | ||||
TNF signaling pathway | ||||
Salmonella infection | ||||
Legionellosis | ||||
NetPath Pathway | IL-7 Signaling Pathway | |||
IL1 Signaling Pathway | ||||
IL4 Signaling Pathway | ||||
TNFalpha Signaling Pathway | ||||
IL5 Signaling Pathway | ||||
Panther Pathway | CCKR signaling map ST | |||
Reactome | Chemokine receptors bind chemokines | |||
G alpha (i) signalling events | ||||
WikiPathways | Cytokines and Inflammatory Response | |||
Spinal Cord Injury | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | Multiple sclerosis: current and future treatment options. Endocr Metab Immune Disord Drug Targets. 2007 Dec;7(4):292-9. |
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